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Twenty 1 Clinic
Twenty 1 Clinic

Twenty 1 Clinic

Med spa in Chicago, IL

Rated 4.7 out of 5 (178 on Google Maps) (opens in a new tab)

Twenty 1 Clinic describes itself as a full-service medspa on Lincoln Avenue in Chicago. The clinic says it focuses on non-invasive treatments and frames beauty as a matter of self-care, confidence and well-being. Its team includes nurse injectors and licensed medical professionals.

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About

Twenty 1 Clinic describes itself as a full-service medspa on Lincoln Avenue in Chicago. The clinic says it focuses on non-invasive treatments and frames beauty as a matter of self-care, confidence and well-being. Its team includes nurse injectors and licensed medical professionals.

The menu is organized into several groups. Advanced Skincare covers a signature facial, a chemical peel, microneedling and PRP skin treatments, and the clinic says microneedling is suitable for all skin types, including sensitive skin. Injectable services include Botox, neurotoxin around the eyes, forehead, or full face with neck or masseter, filler dissolving and facial filler remodeling for areas such as the cheeks, nasolabial folds, under the eyes, jawline, chin and lips.

Full Face Balancing is a customized filler treatment in which the provider chooses the areas and amount of filler. It is offered as a special, a combination with Signature Lips that includes complimentary teeth whitening, and a full package. The clinic notes that this is not a facial slimming, fat-removal or weight-loss treatment. Signature Lips is available in half-syringe, single-syringe and standard options, and the clinic says results are not guaranteed, with a half syringe giving a subtle change and a full syringe sometimes needed for a more noticeable one.

Laser services include hair removal, using FDA-approved lasers with a cooling system, and removal of tattoos and permanent makeup such as eyebrow tattoos, eyeliner and lip blush. Each removal begins with an assessment of ink type, depth and skin tone, often needs several sessions, and can be done with numbing options and cool-down methods. The clinic also offers a medically supervised tirzepatide program billed monthly, with a tailored plan.

Visits begin with a consultation, and Botox and filler pricing depend on the areas treated and the amount needed. Clients who have had filler at another clinic are asked to send clear, recent photos before booking, and a $50 booking deposit holds the appointment time. The clinic also offers a payment plan through Cherry, a buy-now-pay-later service, which adds a $50 fee each time it is used on top of the service price.

The clinic aims to enhance natural features with precision and artistry, with personalized treatment plans built around self-care and confidence.

The clinic space was designed to feel comfortable and relaxing.

Services

Final prices may vary.

Facial and skin-resurfacing options, including a signature facial, chemical peel, microneedling and PRP skin treatment.

  • Chemical Peel $200
  • Microneedling $250
  • PRP Skin $250
  • Signature Facial $250

Customized filler packages that combine full face balancing with lip work, including a whitening add-on in one option.

  • Full Face Balancing + Signature Lips (Complimentary Teeth Whitening) $1,500

Fat dissolving injections for the face, with a set price per session.

  • Fat Dissolving Injections $250

Botox, filler dissolving, facial remodeling, Signature Lips and fat dissolving injections.

  • Neurotoxin Around Eyes $200
  • Facial Slimming (Fat Dissolving Injections) $250
  • Filler Dissolving $250
  • Filler Dissolving 1 vial $250
  • Botox $300
  • Neurotoxin Forehead $350
  • Signature Lips 1/2 syringe $380
  • Signature Lips $500
  • Signature Lips 1 syringe $525
  • Facial Remodeling (Filler) $550
  • Neurotoxin Full Face + Neck or Masseter $800
  • Full Face Balancing Special $1,300
  • Full Face Balancing + Signature Lips $1,500
  • Full Face Balancing Package $3,000
  • Neurotoxin Masseter Price at booking

Botox and facial filler remodeling offered at a range of prices depending on the areas treated.

  • Botox Treatments $300–$1,000
  • Facial Filler Remodeling $550–$3,000

Laser hair removal, plus laser removal of permanent makeup and tattoos.

  • Laser Hair Removal $50
  • Laser PMU Removal $150
  • Laser Tattoo Removal $150
  • Laser Tattoo & PMU Removal $150

Neurotoxin treatments for the eyes, forehead, and full face with neck or masseter.

  • Neurotoxin (Female) Around Eyes $200
  • Neurotoxin (Female) Forehead $350
  • Neurotoxin (Female) Full Face + Neck Or Masseter $800
  • Neurotoxin (Female) Masseter Price at booking

A medically supervised tirzepatide program billed monthly.

  • Tirzepatide Weight Loss (monthly) $600
  • Skin PRP $250
  • Cherry Payment Notice Price at booking
  • Important Notice – Prior Dermal Filler Price at booking

Photos

  • Close-up of glossy pink lips after a lip filler treatment

Meet the team

Their website doesn't list the team, so we don't either.

Highlights
  • Full Face Balancing packages, including a customized filler option and a combination with Signature Lips and complimentary teeth whitening
  • Signature Lips offered in half-syringe, single-syringe and standard sizes
  • Laser tattoo and permanent makeup removal with an ink, depth and skin tone assessment first
  • Medically supervised tirzepatide weight loss program with a tailored plan
  • Cherry payment plans with no hard credit checks and 0% APR options subject to eligibility
Good for
  • First injectable treatment
  • Filler and lip enhancement
  • Neurotoxin for the forehead, eyes or full face
  • Tattoo and permanent makeup removal
  • Sensitive skin
  • Medically supervised weight loss
  • Clients who want a payment plan
Treats
  • Fine lines and forehead lines
  • Under-eye lines
  • Lip volume
  • Facial volume and contour
  • Jawline and chin definition
  • Filler reversal
  • Unwanted tattoos and permanent makeup
  • Unwanted hair
  • Weight loss
  • Skin texture and dullness
Techniques
  • Botox
  • Neurotoxin
  • Dermal filler
  • Hyaluronidase filler dissolving
  • Deoxycholic acid fat dissolving injections
  • Microneedling
  • Chemical peel
  • PRP skin treatment
  • Signature facial
  • Laser hair removal

Products & treatments

  • Revanesse Versa dermal filler
  • Evolysse dermal filler
  • Hyaluronic acid and ceramide skincare in signature facials

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