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Signature Vitality

Signature Vitality

Med spa in Pittsburgh, PA

Rated 5.0 out of 5 (75 on Google Maps) (opens in a new tab)

Signature Vitality is a locally owned IV therapy and wellness studio in Pittsburgh's South Hills, started by registered nurses Megan and Lauren, who built the studio together. The salon describes itself as Pittsburgh's expert IV therapy and wellness studio. The space has free on-site parking, lounge recliners, soft lighting, plants and a 70-inch TV, and is designed to feel private and relaxed rather than like a clinic. Most IV drips and IM boosters can also be given at a client's location across Greater Pittsburgh, with a travel surcharge based on distance; the Vitality Booth, microneedling and facials are available only at the studio. Appointments are offered seven days a week. Studio hours are Monday through Friday, 9 AM to 6 PM, and Saturday, 9 AM to 3 PM, and walk-ins are welcome when nurse availability allows. Book online or call or text 412-440-8702. IV wellness therapy is typically an out-of-pocket expense and the business does not bill insurance, though HSA and FSA cards are accepted. A Letter of Medical Necessity can be requested at a visit for eligible situations, with no guarantee that a plan will accept it.

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About

Signature Vitality is a locally owned IV therapy and wellness studio in Pittsburgh's South Hills, started by registered nurses Megan and Lauren, who built the studio together. The salon describes itself as Pittsburgh's expert IV therapy and wellness studio. The space has free on-site parking, lounge recliners, soft lighting, plants and a 70-inch TV, and is designed to feel private and relaxed rather than like a clinic. Most IV drips and IM boosters can also be given at a client's location across Greater Pittsburgh, with a travel surcharge based on distance; the Vitality Booth, microneedling and facials are available only at the studio. Appointments are offered seven days a week. Studio hours are Monday through Friday, 9 AM to 6 PM, and Saturday, 9 AM to 3 PM, and walk-ins are welcome when nurse availability allows. Book online or call or text 412-440-8702. IV wellness therapy is typically an out-of-pocket expense and the business does not bill insurance, though HSA and FSA cards are accepted. A Letter of Medical Necessity can be requested at a visit for eligible situations, with no guarantee that a plan will accept it.

A first visit begins with a nurse intake that covers goals, medications, allergies and any flags, and the IV is placed afterward. First studio visits usually last 45 to 75 minutes including intake. Standard drips run 45 to 60 minutes, and NAD+ infusions run 2 to 6 hours depending on dose. A registered nurse conducts every session and remains with the client throughout, reviewing health history and vital signs before each infusion. Pennsylvania-licensed registered nurses start and monitor each IV, working under standing orders that a Pennsylvania-licensed supervising physician signs off on. Catheters, tubing, needles, swabs and IV bags are single-use and never reused. Complex protocols are recommended following a free consult.

The IV menu starts with a custom Vital Drip at $105, which includes two Vital Nutrients or one Elite Nutrient, with nutrients chosen at the visit; extra Vital Nutrients are $25 each and Elite Nutrients $50 each. Named drips include the Signature Drip at $230, which the studio describes as its version of the Myers Cocktail, a 30-minute Rapid Refresh Drip at $230, Immune Defense at $255, Radiance at $265, Energy + Focus at $280, and the Benton Drip at $405. NAD+ IV is priced at $250 for 250 mg, $400 for 500 mg, $600 for 750 mg and $800 for 1000 mg, and Niagen NR IM at $350, $650 and $1,200 for the same doses. High-dose vitamin C ranges from $150 for 10 g to $330 for 50 g, high-dose glutathione from $130 for 1.2 g to $300 for 4 g, and BiOcean trace mineral IV is $65 for 125 ml, $125 for 250 ml and $250 for 500 ml. IM booster shots take a few minutes each, cost $25 (Vital) or $50 (Elite), come in packs of six, twelve and twenty-four, and can be added to a drip or a Vitality Booth session; the studio describes them as intended for energy, immunity, skin and recovery. Lab testing, including micronutrient, methyl detox, hormone and gut health panels, is offered after a consult to guide treatment protocols.

Advanced Therapy programs are built through private, consult-based review and address metabolic, recovery, energy, cognitive, hormone and longevity goals. Prescription-only options and custom peptide combinations are covered in consultation. NAD+ infusions, peptide therapy and weight-management medications need an annual telehealth screening with a medical partner, which costs a flat $30 per year. Wellness plans are one-time purchases with no subscription and no automatic charges; sessions don't expire, and members get bundled pricing on drips included in their plan. Foundational Wellness costs $1,295 for eight sessions over four months, and Elite Cellular Performance costs $5,200 for 14 sessions and requires lab onboarding first. Plans can be shared with family members after a nurse clearance, at $30 per person. The Lyme Wellness Support plan is used alongside a Lyme treatment team, requires an intake consultation, and does not replace antibiotic therapy or physician care.

The Vitality Booth is a 20-minute, studio-only session combining red light, dry salt air (halotherapy), aromatherapy and tuned sound. Single sessions cost $50, a six-pack $210 and a twelve-pack $400. The Booth has not been approved by the FDA to treat, cure or prevent any medical condition, and clients who are pregnant, have a respiratory condition or a photosensitive condition are asked to see a physician first. Aesthetic options include microneedling at $600 for a single session, PRP microneedling, PRX Derm Perfexion (a needle-free, roughly 20-minute treatment with no peeling and no downtime), and PRX plus Microneedling at $550 for a single session. Microneedling and facials include PRP and are performed by licensed aesthetics providers. For events, the studio provides wedding IV for brides, grooms and wedding parties, either at the studio or mobile to a venue, hotel or home. A $500 minimum deposit secures a date, and a service contract follows on confirmation. Wedding IV group pricing starts at $135 per person; the Wedding Party package for two to four guests starts at $560, and the Full Experience for five to eight guests starts at $1,050. Parties of four to six receive 10% off, and parties of six to ten receive 15% off; nine or more guests receive a custom quote. Travel fees may apply to locations more than 20 miles away. According to the website, Pittsburgh Steelers defensive tackle Keeanu Benton is a client for IV therapy, NAD+ and the Vitality Booth.

Built around care rather than a transaction, with a nurse intake, health review and screening before any infusion.

Designed to feel like a private, relaxed space rather than a clinic, with lounge recliners, soft lighting, plants and a 70-inch TV.

Specials & promotions

  • 10% off for groups of 4-6 guests

    Group rates for 4-6 guests

    On their website as of Nov 1, 2026 · Where we saw it

  • 15% off for groups of 6-10 guests

    Group rates for 6-10 guests

    On their website as of Nov 1, 2026 · Where we saw it

  • Complimentary couple and honor attendant upgrades

    Large parties of 9+ guests

    On their website as of Nov 1, 2026 · Where we saw it

  • The Full Experience wedding package at $135 per person

    $135

    5-8 guests; couple Glutathione push included

    On their website as of Nov 1, 2026 · Where we saw it

  • Calm, Sleep & Stress plan: 8 sessions

    $1,585

    Eight sessions over three months; saves $545

    On their website as of Nov 1, 2026 · Where we saw it

  • Energy & Burnout plan: 12 sessions

    $2,140

    Twelve sessions over six months; saves $705

    On their website as of Nov 1, 2026 · Where we saw it

  • Foundational Wellness plan: 8 sessions

    $1,295

    Eight sessions over four months; saves $580

    On their website as of Nov 1, 2026 · Where we saw it

  • Vitality Booth 6-session pack

    $210

    $35 per session

    On their website as of Nov 1, 2026 · Where we saw it

  • Vitality Booth 12-session pack

    $400

    $33 per session

    On their website as of Nov 1, 2026 · Where we saw it

  • Microneedling 3-session pack

    $1,500

    Save $100 each

    On their website as of Nov 1, 2026 · Where we saw it

  • Microneedling 6-session pack

    $2,700

    Save $150 each

    On their website as of Nov 1, 2026 · Where we saw it

  • PRX Signature series of 4

    $1,100

    Save $200

    On their website as of Nov 1, 2026 · Where we saw it

  • PRX + Microneedling series of 4

    $1,950

    Save $250

    On their website as of Nov 1, 2026 · Where we saw it

Services

Final prices may vary.

Custom and named IV drips, from a $105 Vital Drip base to specialty blends, with add-on nutrients available.

  • Vital Nutrient add-on $25
  • Elite Nutrient add-on $50
  • Vital Drip $105
  • Hydrate $155
  • Pico IV $175
  • Calm + Restore $200
  • Athletic Recovery $205
  • Bounce Back $205
  • Rapid Refresh Drip $230
  • Rapid Refresh Drip EXPRESS $230
  • The Signature Drip $230
  • NAD+ Therapy $250+
  • Immune Defense $255
  • Radiance $265
  • Breathe $275
  • Energy + Focus $280
  • Benton Drip $405

Vital and Elite IM booster injections and multi-packs, given at the studio in a few minutes each.

  • IM Vital Booster $25
  • Vitamin B-12 $25–$50
  • IM Elite Booster $50
  • Nad+ / Nr Price at booking

NAD+ IV and Niagen NR IM at several dose levels, with infusion time depending on the dose.

  • NAD+ IV 250 mg $250
  • Niagen NR IM 250 mg $350
  • NAD+ IV 500 mg $400
  • NAD+ IV 750 mg $600
  • Niagen NR IM 500 mg $650
  • NAD+ IV 1000 mg $800
  • Niagen NR IM 1000 mg $1,200
  • NAD+ At-Home Program Price at booking
  • Niagen (NR) Price at booking

Consult-based programs for metabolic, recovery, energy, cognitive, hormone and longevity goals, reviewed privately.

  • Cognitive & Mood Price at booking
  • Energy & Performance Price at booking
  • Hormone & Wellness Price at booking
  • Longevity & Immune Price at booking
  • Metabolic & Body Composition Price at booking
  • Peptide Therapy Price at booking
  • Recovery & Repair Price at booking

Bundled one-time wellness plans of sessions over set schedules, with member pricing on included drips.

  • Foundational Wellness $1,295
  • Immune Support $1,390
  • Calm, Sleep & Stress $1,585
  • Energy & Burnout $2,140
  • Mind & Mood Restoration Price at booking

Larger longevity and performance plans, including a lab-led cellular reset and an elite performance plan.

  • Longevity & Cellular Reset $4,600
  • Elite Cellular Performance $5,200
  • Lyme Wellness Support Price at booking
  • Post-Viral Recovery Price at booking

Support plans for concerns such as allergy and sinus, gut health, migraine, perimenopause and fertility and hormones.

  • Allergy, Sinus & Respiratory $1,030
  • Gut Reset & Digestive $1,195
  • Migraine Support $1,295
  • Perimenopause Wellness $1,495
  • Fertility & Hormone Support $1,695
  • Thyroid Harmony Price at booking

Plans for tick-exposure wellness, perimenopause balance, thyroid support and mental wellness.

  • Mental Wellness Support Price at booking
  • Perimenopause Balance Price at booking
  • Thyroid Support Price at booking
  • Tick-Exposure Wellness Support Price at booking

High-dose vitamin C and glutathione protocols, and BiOcean trace mineral IV.

  • BiOcean IV 125 ml $65
  • BiOcean IV 250 ml $125
  • High Dose Glutathione 1.2 g $130
  • High Dose Glutathione (GSH) 1.2 Grams $130
  • High Dose Vitamin C 10 g $150
  • High Dose Vitamin C 10 Grams $150
  • High Dose Glutathione 2 g $180
  • High Dose Glutathione (GSH) 2 Grams $180
  • High Dose Vitamin C 20 g $200
  • High Dose Vitamin C 20 Grams $200
  • BiOcean IV 500 ml $250
  • High Dose Glutathione 3 g $250
  • High Dose Glutathione (GSH) 3 Grams $250
  • High Dose Vitamin C 30 g $280
  • High Dose Vitamin C 30 Grams $280
  • High Dose Glutathione 4 g $300
  • High Dose Glutathione (GSH) 4 Grams $300
  • High Dose Vitamin C 50 g $330
  • High Dose Vitamin C 50 Grams $330

Microneedling, PRP microneedling, PRX Derm Perfexion and combination treatments, performed at the studio.

  • PRX-C Glow single $350
  • PRX + Microneedling single $550
  • Microneedling single session $600
  • PRX Signature Series of 4 $1,100
  • PRX Signature single $1,100
  • Microneedling 3 pack $1,500
  • Advanced PRX + Microneedling Series of 4 $1,950
  • PRX + Microneedling Series of 4 $1,950
  • Microneedling 6 pack $2,700
  • PRP Microneedling Price at booking
  • Microneedling Price at booking
  • PRX Derm Perfexion Price at booking

The Vitality Booth, offered as single sessions and packs at the studio only.

  • Vitality Booth single session $50
  • Vitality Booth 6 pack $210
  • Vitality Booth 12 pack $400

Lab panels such as micronutrient testing, hormone panels and gut health testing, used after a consult.

  • Gut Health Testing Price at booking
  • Hormone Panels Price at booking
  • Methyl Detox Profile lab panel Price at booking
  • Micronutrient Testing Price at booking

Athlete recovery consults and programs, plus wedding, bridal, bachelor and bachelorette and corporate group services.

  • Athlete Recovery Price at booking
  • Wedding IV Price at booking
  • Wedding Party package 2-4 guests $560
  • Wedding Full Experience 5-8 guests $1,050
  • NAD+ IV 250mg $250
  • NR / Niagen (IM) 250mg $350
  • NAD+ IV 500mg $400
  • NAD+ IV 750mg $600
  • NR / Niagen (IM) 500mg $650
  • NAD+ IV 1000mg $800
  • NR / Niagen (IM) 1000mg $1,200
  • Skin, Hair & Glow $1,395
  • Athletic Recovery Plan $1,695
  • Additional Vital $25
  • Additional Elite $50
  • B-Complex $25/unit
  • Vitamin C $25/unit
  • Athlete Recovery Consult Price at booking
  • Bridal Experience Price at booking
  • Weight Management Consult Price at booking
  • Wellness Coaching Consult Price at booking
  • ALA $50
  • AminoMultiplex (Arginine, Lysine, Proline, Glutamine) $50
  • Carnitine $50
  • Magnesium Chloride $50
  • NAC $50
  • Trace Elements (Selenium, Manganese, Copper, Zinc) $50
  • Tri-Immune (Glutathione, C, Zinc) $50
  • Zinc $50
  • Vital Nutrients $25/unit
  • Elite Nutrients $50/unit
  • Bachelor & Bachelorette Price at booking
  • Bridal & Wedding IV Price at booking
  • Corporate Wellness Price at booking
  • Vital Boost B-12 $25
  • Vital Boost B-Complex $25
  • Vital Boost Carnitine $25
  • Vital Boost Toradol / Zofran $25
  • Vital Boost Tri-Immune x1 $25
  • Elite Boost AminoMultiplex x2 $50
  • Elite Boost Biotin $50
  • Elite Boost CoQ10 $50
  • Elite Boost Lipo MIC + B-12 $50
  • Elite Boost Tri-Immune x2 $50
  • Elite Boost Vitamin D3 $50
  • Vital Boost 6 Pack $125
  • Vital Boost 12 Pack $240
  • Elite Boost 6 Pack $250
  • Vital Boost 24 Pack $475
  • Elite Boost 12 Pack $480
  • Elite Boost 24 Pack $950
  • Cellular Micronutrient Testing Price at booking
  • Hormone Panel Price at booking
  • Methyl Detox Profile Price at booking
  • B-12 Price at booking
  • Biotin Price at booking
  • CoQ10 Price at booking
  • Glutathione Price at booking
  • Lipo MIC Price at booking
  • NAD+ Shot Price at booking
  • Tri-Immune Price at booking
  • Vitamin D3 Price at booking
  • Dissolvd Strips Price at booking
  • Facials & PRP Microneedling Price at booking
  • Programs & At-Home Price at booking
  • Specialty IVs Price at booking
  • Weight Management Price at booking
  • Wellness Coaching Price at booking
  • Wellness Plans Price at booking
  • B-12 Shot $25
  • NAD+ Price at booking
  • PRX-C Glow $350
  • PRX + Microneedling $550
  • Microneedling (PRP) Price at booking
  • Six Pack $210
  • Twelve Pack $400
  • B-12 (Methylcobalamin) $25
  • B-Complex (B1, B2, B3, B5, B6) $25
  • Glutamine $25
  • Lysine $25
  • Proline $25
  • Taurine $25
  • Toradol $25
  • Vitamin C (Ascorbic Acid) $25
  • Zofran $25
  • The Wedding Party $560+
  • The Full Experience $1,050+
  • Large Party Price at booking
  • The Radiance Drip $265
  • Aesthetic & Performance Price at booking
  • Condition Support Price at booking
  • Everyday Wellness Price at booking
  • Restoration & Longevity Price at booking
  • IM Boosters Price at booking
  • Mobile Services Price at booking
  • Peptide Consults Consultation
  • Specialty IV Drips Price at booking
  • Vitality Booth Price at booking

Photos

  • Halotherapy unit mounted on a wall in a red-lit room

Meet the team

Team members listed on their website. Individual roles, credentials, and current employment have not been independently verified.signaturevitality.net (opens in a new tab)

Highlights
  • Every IV, IM injection and NAD+ infusion is run by a registered nurse who stays for the whole session
  • Custom Vital Drip starting at $105, with nutrients chosen at the visit
  • Vitality Booth: a 20-minute studio-only session combining red light, dry salt air, aromatherapy and tuned sound
  • Wellness plans as one-time purchases, with sessions that never expire
  • PRX Derm Perfexion, a needle-free treatment with no peeling and no downtime
  • Supplements dispensary managed through Fullscript
Good for
  • first IV visit
  • custom hydration
  • athletes and athletic recovery
  • wedding parties and bridal groups
  • bachelor and bachelorette groups
  • corporate wellness groups
  • mobile visits across Greater Pittsburgh
  • walk-ins when nurse availability allows
  • clients who want a private, relaxed setting
  • clients who prefer a provider-guided plan
Treats
  • energy and burnout
  • sleep and stress
  • immune support
  • skin and radiance
  • hair
  • gut health
  • migraine support
  • allergy, sinus and respiratory support
  • perimenopause
  • thyroid support
Techniques
  • IV drips
  • IM booster injections
  • NAD+ infusion
  • Niagen (NR)
  • High-dose vitamin C
  • High-dose glutathione
  • BiOcean trace mineral therapy
  • Peptide therapy
  • Red light therapy
  • Halotherapy (dry salt air)

Products & treatments

  • Fullscript supplements dispensary
  • BiOcean
  • PRX Derm Perfexion
  • Niagen
  • Lipo MIC (methionine, inositol and choline)
  • Tri-Immune (glutathione, vitamin C and zinc)
  • Vital Nutrients
  • Elite Nutrients

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