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Signal Skin Science
Signal Skin Science

Signal Skin Science

Spa in Denver, CO

Rated 5.0 out of 5 (141 on Google Maps) (opens in a new tab)

Signal Skin Science is a newer Denver studio opened by its owner, Sameera. It is set up as a facial, skin care and wellness spa with free on-site parking, and gift cards are sold through the website. Clients can book online or by phone or text at 720-334-8030.

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About

Signal Skin Science is a newer Denver studio opened by its owner, Sameera. It is set up as a facial, skin care and wellness spa with free on-site parking, and gift cards are sold through the website. Clients can book online or by phone or text at 720-334-8030.

The spa calls its philosophy holistic-meets-medical, based on the view that skin care goes beyond cosmetics because skin reflects what is happening inside the body. According to the spa, its name comes from cellular signaling pathways, and the team works to interpret the signals behind visible skin concerns. Treatments are carried out with medical-grade equipment and protocols. The spa says it directs its budget toward treatments, products and education rather than advertising. Medspa, injectable and IV nutrition therapy services are all overseen by Dr. Michael Iannotti, the Medical Director.

Facials are customized by the esthetician, who chooses from a range of products and treatments for each client's skin. Clients pick the session length, and facial sessions typically run 60 to 90 minutes. A Virtual Skin Consultation reviews current concerns and routine to build a home regimen and an in-office plan, and its cost can be applied to a facial or product purchase.

Clinical skin services target acne scarring, lines and wrinkles, loss of firmness, and sun damage or hyperpigmentation, usually with pre- and post-treatment skin care recommendations. Chemical peels are chosen by skin type and concern and carry some downtime, including peeling, dryness or sensitivity. Peels are not offered to first-time clients, and skin needs preparation with home care beforehand. The Enlighten Peel requires a prior consultation.

It is booked directly through NOVALUNE LASER rather than through the spa. Pricing is described as fair and inclusive, with no additional tip required. New clients receive a complimentary consultation and $20 off their first facial. Online appointments need at least 24 hours' notice, and same-day openings are handled by phone or text.

Combines holistic and medical thinking, with each treatment customized by the esthetician to the client's skin and needs.

Specials & promotions

  • $20 off your first facial appointment

    For new customers

    On their website as of Oct 29, 2026 · Where we saw it

  • Complimentary consultation for new customers

    For new customers

    On their website as of Oct 29, 2026 · Where we saw it

Services

Final prices may vary.

Acupuncture initial consultations and follow-up visits, with treatments of 60 or 90 minutes and options such as moxibustion or cupping.

  • Acupuncture Price at booking

Laser hair removal for bikini and body areas, including the Brazilian, buttocks, chest, back and stomach.

  • Abdomen Price at booking
  • Areolas Price at booking
  • Bikini/Extended Bikini Price at booking
  • Brazilian Price at booking
  • Buttocks Price at booking
  • Chest Price at booking
  • Full/Half Back Price at booking
  • Inner Buttocks Price at booking
  • Shoulders Price at booking
  • Stomach Price at booking
  • Laser Hair Removal Price at booking

Peels for acne, hyperpigmentation, sun damage, scarring and fine lines, including BioRePeel, custom peels and the Enlighten Peel.

  • BioRePeel Price at booking
  • Chemical Peels Price at booking
  • Custom Chemical Peel Price at booking
  • Enlighten Peel De-Pigmentation System Price at booking

Clinical treatments for acne scarring, lines, firmness and sun damage, such as GlowTox, microneedling, hydrodermabrasion and radio frequency.

  • Thermoclear Radio Frequency Treatment $75
  • AquaDiamond Hydrodermabrasion Treatment Price at booking
  • Clinical Skin Services Price at booking
  • GlowTox Micro-infusion Facial Price at booking
  • Microneedling Collagen Induction Therapy Price at booking
  • Microneedling Collagen Induction Therapy Treatment Price at booking

Targeted facials for acne and for rejuvenation, with extractions, LED and hydrating steps.

  • Acne Facial Price at booking
  • Rejuvenating Facial Price at booking

Laser hair removal for the full face, partial face, neck, beard, lip and other facial areas.

  • Beard Price at booking
  • Cheeks Price at booking
  • Chin Price at booking
  • Ears Price at booking
  • Forehead Price at booking
  • Front/Back of Neck Price at booking
  • Full Face Price at booking
  • Full/Partial Neck Price at booking
  • Partial Face Price at booking
  • Upper Lip Price at booking

Massage-based treatments including face sculpting with buccal massage, gua sha facials and facial massage.

  • Face Sculpting + Buccal Massage Price at booking
  • Facial Massage Price at booking
  • Gua Sha Facial Price at booking

Custom facials, back facials, dermaplane express, LED light therapy, liquid microneedling and virtual skin consultations.

  • Back Facial Price at booking
  • Dermaplane Express Price at booking
  • Facials Price at booking
  • LED Light Therapy Treatment Price at booking
  • Trio Liquid Microneedling Treatment Price at booking
  • Virtual Skin Consultation Price at booking

General laser hair removal across body areas, face and neck, bikini, and legs and arms.

  • Full Arms Price at booking
  • Full Feet Price at booking
  • Full Leg Price at booking
  • Lower Arms Price at booking
  • Lower Leg Price at booking
  • Toes Price at booking
  • Underarm Price at booking
  • Upper Arms Price at booking
  • Upper Leg Price at booking

Photos

  • Before and after close-up of acne treatment showing reduced redness and bumps on cheek
  • Before and after facial showing smoother, firmer skin along jawline and chin
  • Before and after brightening facial showing more even, glowing skin tone
  • Before and after microneedling showing smoother, clearer cheek texture
  • Before and after acne treatment showing clearer skin with fewer breakouts
  • Before and after acne treatment showing reduced redness and breakouts on cheek
  • Before and after acne treatment showing far fewer breakouts and calmer skin
  • Before and after men's facial showing calmer, clearer forehead and cheeks
  • Before and after men's facial showing reduced redness and smoother skin
  • Before and after acne scarring treatment with a blue device, showing clearer skin
  • Before and after sensitive skin facial showing calmer, more even skin
  • Before and after skin tag removal on forehead area

Meet the team

Team members listed on their website. Individual roles, credentials, and current employment have not been independently verified.signalskinscience.com (opens in a new tab)

Highlights
  • GlowTox Micro-infusion Facial, with cleansing, analysis, dermaplane, a growth factor solution and an LED finish, and no downtime
  • Microneedling Collagen Induction Therapy with numbing and AnteAGE growth factors, with a post-care kit and an optional growth factor upgrade
  • Enlighten Peel de-pigmentation system, a 28-day non-inflammatory treatment aimed at pigmentation, pores and fine lines
  • Gua Sha Facial using a patented gua sha tool, finished with vacuum cupping
  • Virtual skin consultations for planning an at-home routine
  • Laser hair removal booked through NOVALUNE LASER
Good for
  • first facial
  • acne-prone skin
  • dry or dull skin
  • sun-damaged skin
  • pigmentation concerns
  • planning an at-home skin care routine
  • clients interested in facial massage for jaw tension
  • gift buyers
  • laser hair removal
Treats
  • acne
  • acne scarring
  • hyperpigmentation
  • sun damage
  • fine lines and wrinkles
  • sagging or loss of firmness
  • dryness
  • dullness
  • unwanted hair
  • spider capillaries, skin tags, milia and sun spots
Techniques
  • custom facials
  • dermaplaning
  • LED light therapy, blue and red light
  • Celluma LED
  • microcurrent
  • high frequency
  • microneedling
  • liquid microneedling
  • chemical peels
  • BioRePeel biphasic peel with AHAs

Products & treatments

  • Skinbetter
  • LeMieux Skin Care
  • AnteAGE
  • GlowTox solution

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