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Pyo Clinic
Pyo Clinic
Pyo Clinic

Pyo Clinic 02

Med spa in Upland, CA · 2 locations

Rated 5.0 out of 5 (1 on Google Maps) (opens in a new tab)

Pyo Clinic brings family medicine and physician-led aesthetic treatments together in one practice, with two clinics in Fullerton and Upland. According to the clinic, it has served more than 5,400 patients as of September 2026. It describes its approach as clinical care paired with a personal touch.

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About

Pyo Clinic brings family medicine and physician-led aesthetic treatments together in one practice, with two clinics in Fullerton and Upland. According to the clinic, it has served more than 5,400 patients as of September 2026. It describes its approach as clinical care paired with a personal touch.

On the medical side, the clinic handles annual physicals, wellness screenings, pre-employment and school physicals, and blood pressure and cholesterol checks. Same-day visits cover colds, flu and COVID, allergies, asthma and sinus issues, minor skin infections and rashes, stomach complaints, and pregnancy testing. Ongoing care covers hypertension, diabetes, high cholesterol, thyroid disorders and digestive concerns such as GERD and IBS. EKGs are done in clinic, and lab work and imaging are referred to outside partners. Senior services include Medicare wellness visits, fall risk and cognitive assessments, and medication reviews. Weight management offers physician-guided plans with diet and lifestyle coaching and progress monitoring, and medication-based options for eligible patients.

The aesthetic side starts with a free consultation, where the team helps choose a treatment based on skin goals, budget and lifestyle. Acne care includes customized skincare using professional-grade products, the JetPeel Facial, and prescription-based plans that can include oral or topical medication when needed. Injectable options are Botox and Xeomin, both neurotoxins used for expression lines. Rejuran boosters address elasticity, hydration, healing and tone, and needle-free PRP and skin boosters are offered for skin and hair. Venus Viva MD and DiamondPolar are radiofrequency treatments for collagen and firmness, and according to the website, Venus Viva MD is often paired with Rejuran boosters.

Practical details: the Fullerton clinic is open Tuesday through Saturday, including Saturday appointments, and the Upland clinic is open Monday through Friday. Listed hours at both are 9 AM to 5 PM. Booking ahead is recommended. The clinic accepts most major insurance plans and offers self-pay options. The insurance list is not exhaustive and may change, so patients should confirm coverage with their insurer before an appointment. Some plans are accepted only with specific providers, and Medicare plans are accepted through a medical group that must list Dr. Howard Pyo as the primary care physician. Staff speak English, Spanish, Korean, Indonesian and Tagalog.

Physician-led care across both medical and aesthetic services, with each treatment chosen around the patient's skin goals, budget and lifestyle.

Services

Final prices may vary.

Customized skincare regimens, the JetPeel Facial, and prescription-based plans for acne.

  • Customized Skincare Regimens Price at booking
  • JetPeel Facial Price at booking
  • Prescription-Based Treatment Plans Price at booking
  • Venus Viva MD Price at booking

Radiofrequency options, including Venus Viva MD and DiamondPolar, aimed at collagen and firmness.

  • DiamondPolar Price at booking

Botox and Xeomin, FDA-approved neurotoxin options for expression lines.

  • Botox Price at booking
  • Xeomin Price at booking

Needle-free PRP for skin and hair, plus a needle-free skin booster and a scalp booster.

  • Needle-Free Hair & Scalp Booster Price at booking
  • Needle-Free PRP Hair Price at booking
  • Needle-Free PRP Skin Price at booking
  • Needle-Free Skin Booster Price at booking

Rejuran boosters for elasticity, hydration, soothing, and brightening and evening tone.

  • Rejuran Healing Essence Price at booking
  • Rejuran Skin Booster Price at booking
  • Rejuran Tone-Up Booster Price at booking

Same-day care for colds, flu and COVID, allergies, asthma, sinus issues, minor skin infections, stomach complaints and pregnancy testing.

  • Allergies, asthma, and sinus issues Price at booking
  • Cold, flu, and COVID visits Price at booking
  • Minor skin infections and rashes Price at booking
  • Pregnancy testing Price at booking
  • Stomach aches, nausea, and food poisoning Price at booking

Ongoing care for hypertension, diabetes, high cholesterol, thyroid disorders and digestive concerns.

  • Diabetes management Price at booking
  • GERD, IBS, and digestive concerns Price at booking
  • High cholesterol management Price at booking
  • Hypertension management Price at booking
  • Thyroid disorders Price at booking

In-clinic EKGs, with lab work and imaging referred to outside partners.

  • EKGs Price at booking

Annual physicals, wellness screenings, blood pressure and cholesterol checks, pre-employment and school physicals, and lifestyle and nutrition counseling.

  • Annual physical exams Price at booking
  • Blood pressure & cholesterol checks Price at booking
  • Lifestyle and nutrition counseling Price at booking
  • Pre-employment & school physicals Price at booking
  • Wellness screenings Price at booking

Medicare wellness visits, fall risk and cognitive assessments, and medication reviews with chronic care coordination for older adults.

  • Fall risk and cognitive assessments Price at booking
  • Medicare wellness visits Price at booking

Physician-guided weight loss plans with diet and lifestyle coaching, progress monitoring, and medication-based options for eligible patients.

  • Physician-guided weight loss plans Price at booking

Photos

  • Bright reception area with marble front desk and Pyo Clinic sign
  • Before and after facial skin result from Venus Viva and Rejuran sessions
  • Side-profile before and after of jowl and cheek treatment
  • Side-profile before and after of skin tightening and contour
  • Scalp and hair before and after three Jetpeel sessions
  • Forehead before and after one Botox session
  • Forehead before and after 20 units of Xeomin
  • Forehead acne and skin before and after one Venus Viva session
  • Side-profile skin before and after one Venus Viva session
  • Before and after neck results from three Diamond Polar sessions
  • Before and after neck and jawline results from Diamond Polar treatment
  • Before and after facial skin results from Venus Viva and Rejuran sessions

Meet the team

Their website doesn't list the team, so we don't either.

Highlights
  • Family medicine and physician-led aesthetic treatments under one roof at two locations
  • Free consultation to help choose a treatment based on skin goals, budget and lifestyle
  • Prescription-based acne treatment plans, with oral or topical medication if needed
  • Needle-free PRP and skin booster options for skin and hair
  • Rejuran boosters and Venus Viva MD radiofrequency treatment, often paired together
  • Accepts most major insurance and offers self-pay options
Good for
  • acne treatment
  • first consultation to choose a treatment
  • patients wanting primary care and aesthetic treatment in one practice
  • same-day sick visits
  • school and pre-employment physicals
  • Medicare patients
  • self-pay patients
  • weight management plans
  • Spanish, Korean, Indonesian and Tagalog speakers
Treats
  • acne
  • expression lines
  • uneven skin tone
  • elasticity and hydration
  • skin firmness
  • hair growth support
  • scalp health
  • minor skin infections and rashes
  • hypertension
  • diabetes
Techniques
  • neurotoxin injections
  • needle-free PRP
  • needle-free skin boosters
  • scalp exfoliation with serums
  • JetPeel high-pressure oxygen and saline treatment
  • nano-fractional radiofrequency
  • non-invasive radiofrequency
  • prescription oral and topical acne medication
  • physician-guided weight loss plans
  • EKG

Products & treatments

  • Botox
  • Xeomin
  • Rejuran
  • Venus Viva MD
  • DiamondPolar
  • JetPeel

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