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Optimize U
Optimize U

Optimize U

Med spa in Clarksville, IN

Rated 5.0 out of 5 (86 on Google Maps) (opens in a new tab)

Optimize U offers hormone therapy, wellness services, and aesthetic treatments, and serves patients in Kentucky and Indiana. The company describes its mission as making a difference in the lives of people looking for better health and wellness, and it names accessibility, affordability, excellence, and empowerment as its core values. Jessica Matis, one of its practitioners, helped bring the company to Louisville.

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About

Optimize U offers hormone therapy, wellness services, and aesthetic treatments, and serves patients in Kentucky and Indiana. The company describes its mission as making a difference in the lives of people looking for better health and wellness, and it names accessibility, affordability, excellence, and empowerment as its core values. Jessica Matis, one of its practitioners, helped bring the company to Louisville.

The first step for new patients is contacting the office by phone or web form. Blood labs are then drawn at the clinic or at any LabCorp location, and a provider reviews the results at an appointment. The patient and provider talk through treatment options and choose a plan that fits the patient's goals. Hormone therapy is priced all-in-one, covering hormone optimization, ongoing lab work, office visits, supplies, and recovery. Consultations can run as long as needed so questions get answered. Medications are shipped to the patient's home in a discreet box, and refills can be requested through the patient portal or by telling staff.

The aesthetic menu includes neurotoxin injectables (Botox, Dysport, and Jeauvu) for forehead lines, lines between the eyes, and crow's feet, as well as Kybella for fat under the chin and Sculptra, a poly-L-lactic acid filler. Dermal fillers are made with hyaluronic acid by Restylane and Juvederm, and are offered for lips, cheeks, chin, and jaw line, plus an 8-point lift. Microneedling comes with a brightening serum, growth factor, or platelet-rich plasma drawn from the patient's own blood, and an exosome or dermaplaning add-on is available. Chemical micropeels use glycolic, lactic, and phytic acids. The business says its Sentient Sculpt body contouring treatment is FDA cleared for reduction of cellulite and involves no downtime.

The wellness menu covers IV therapy blends, a NAD+ infusion named Cellular Energy Reset, peptides, cold plunge sessions, infrared saunas and compression treatment. Monthly membership tiers are priced at 99, 199 and 399 dollars. Cherry is an accepted payment method. Telemedicine consultations are offered in a limited form, and only for people who are in Kentucky when the call takes place.

Care starts with labs and a provider visit, and treatment plans are shaped by each patient's symptoms and goals rather than a fixed package.

Specials & promotions

  • $150 off any package of 3 microneedling treatments

    $400

    Package of 3 treatments with Brightening Serum

    On their website as of Nov 1, 2026 · Where we saw it

Services

Final prices may vary.

Dermaplaning and Exosome Regenerative Complex can be added to other treatments.

  • Dermaplane $50/unit
  • Exosome Regenerative Complex $100/unit

Sentient Sculpt, a non-invasive body contouring treatment, priced per area after a free consultation.

  • Sentient Sculpt Price at booking

AHA gel peels for exfoliation, including options for sensitive skin, with dermaplaning available as an add-on.

  • Dermaplane add on $50
  • The Glow Up $100
  • Sensitive Sally $125
  • Turn Back Time $125

Dermal fillers for cheeks, chin, jaw line, and lips, plus an 8-point lift.

  • Cheeks Filler $650
  • Chin Filler $650
  • Jaw Line Filler $650
  • Lips Filler $650
  • 8-Point Lift $1,200
  • Cheeks $650–$800
  • Chin $650
  • Jaw Line $650
  • Lips $650

Hormone replacement therapy for men and women, planned from testing and adjusted to individual goals and symptoms.

  • Hormone Replacement Therapy Price at booking

Neurotoxin injections for lines, Kybella for fat under the chin, and Sculptra for lost collagen.

  • Dysport $4
  • Botox $12
  • Jeauvu $12
  • Kybella $600
  • Sculptra $650

Vitamin and mineral IV blends and a 4 to 6 hour NAD+ infusion.

  • Anti-Aging Iv $135
  • Athlete Performance Blend Iv $135
  • Focus & Clarity Iv $135
  • Hangover Cure Iv $135
  • Immune Boost Iv $135
  • Optimal Choice Blend Iv $135
  • CELLULAR ENERGY RESET (NAD+ infusion) $500
  • Peptides Price at booking

Microneedling with brightening serum, growth factor, or platelet-rich plasma, with add-on options.

  • Dermaplane add-on (microneedling) $50
  • Exosome Regenerative Complex add-on $100
  • Microneedling w/ Brightening Serum $400
  • Microneedling w/ Growth Factor $500
  • Microneedling w/ PRP $550

Cold plunge sessions, infrared saunas, and compression treatment.

  • Cold Plunge Price at booking
  • Compression Price at booking
  • Infrared Saunas Price at booking

A wellness grouping that brings together hormone therapy, recovery, peptides and IV therapy, and aesthetics.

  • Aesthetics Price at booking
  • Peptides & IV Therapy Price at booking

Photos

  • client seated in infrared sauna
  • client relaxing in compression boot recliner
  • two staff seated together in white room
  • Before and after abdomen body sculpting results on a client
  • Before and after abdomen body sculpting results on a client
  • Before and after back body sculpting results
  • Before and after buttock cellulite treatment results

Meet the team

Team members listed on their website. Individual roles, credentials, and current employment have not been independently verified.optimizeulouisville.com (opens in a new tab)

Highlights
  • All-in-one hormone therapy pricing that includes labs, visits, supplies, and recovery
  • Medications delivered discreetly to the patient's home, with refills requested through the patient portal
  • Sentient Sculpt body contouring listed with no downtime and aftercare guidance
  • Botox described by the business as the first FDA-approved neurotoxin
  • IV blends listed at 135 dollars for members and 150 dollars for non-members
  • Membership plans listed at 99, 199, and 399 dollars per month
Good for
  • Hormone therapy for men and women of all ages
  • Patients who want a plan built on lab work and symptoms
  • Non-surgical body contouring with no downtime
  • Neurotoxin and filler appointments
  • Patients in Kentucky and Indiana
  • Telemedicine consultations for patients physically in Kentucky
Treats
  • Forehead lines
  • Lines between the eyes
  • Crow's feet
  • Fat under the chin
  • Cellulite
  • Signs of aging and wrinkles
  • Lip volume
  • Low energy and fatigue
  • Low libido
  • Sleep
Techniques
  • Hormone replacement therapy with bio-identical hormones
  • Neurotoxin injections
  • Dermal fillers with hyaluronic acid
  • Kybella injections
  • Sculptra injections
  • Microneedling
  • Platelet-rich plasma microneedling
  • Exosome Regenerative Complex
  • Chemical micropeels
  • Dermaplaning

Products & treatments

  • Botox
  • Dysport
  • Jeauvu
  • Restylane
  • Restylane Kysse
  • Juvederm
  • Sculptra
  • Exosome Regenerative Complex
  • The Glow Up peel
  • Sensitive Sally peel
  • Turn Back Time peel
  • Cellular Energy Reset
  • Anti-Aging IV
  • Athlete Performance Blend IV
  • Focus and Clarity IV
  • Hangover Cure IV
  • Immune Boost IV
  • Optimal Choice Blend IV

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